In dependence of the parasites we formed three different forms of Malaria- Three-day malaria, Tropical Malaria and Four-day Malaria. However in spite of the way of infection, the Malaria can be divided in dependence of the illness symptoms and length. The Cerebral Malaria is one of the most dangerous types of the virus. The children are more vulnerable to this type of Malaria and it may cause neurological damage and impairment of cognition. Cerebral Malaria is also related to graying of the retina, which is a useful symptom to distinguish malaria from other fevers.
The acute cases of Malaria are almost always caused by infection with Plamodium falciparum and usually occur between 6 and 14 days after the infection. If not treated accurately and fast the Acute Malaria can lead to coma and death. The most vulnerable for this type of Malaria are the young children and pregnant women. Such cases may happen and develop very quickly, leading to death within hours or days. The possible symptoms of Acute Malaria are including splenomegaly, cerebral ischemia, hepatomegaly, severe headache, hypoglycemia, and hemoglobinuria with renal failure. The renal failure can lead to liver fever, where hemoglobin enters the urine. In acute malaria mortality may exceed 20%, even with intensive treatment and care. In the highly endemic areas, the treatment is often unsatisfactory and mortality of the total cases of malaria may reach 10%.
The Chronic malaria is seen in infections with Plasmodium vivax and Plasmodium оvale, but not with Plamodium falciparum. This disease may recur months or years after initial development because of the presence of latent parasites in the liver, which are not visible in the microscope medical test. For this reason, it can be concluded that the disease is completely cured when parasites disappear from the blood. Usually the incubating period of Malaria infected person is over an year, because sometimes the disease recur again after a few months and even year.